| 18 Sep 2021 | Ross High (EL1) (A) | L 7-62 |
| 25 Sep 2021 | Portobello (EL1) (H) | L 7-59 |
| 9 Oct 2021 | Hawick Harlequins (EL1) (A) |
| 16 Oct 2021 | Broughton (EL1) (H) |
| 23 Oct 2021 | Royal High (EL1) (A) |
| 30 Oct 2021 | Haddington (EL1) (H) |
| 27 Nov 2021 | Linlithgow (EL1) (A) |
| 11 Dec 2021 | Forrester (EL1) (A) |
| 8 Jan 2022 | Ross High (EL1) (H) |
| 15 Jan 2022 | Portobello (EL1) (A) |
| 22 Jan 2022 | Hawick Harlequins (EL1) (H) |
| 29 Jan 2022 | Broughton (EL1) (A) |
| 19 Feb 2022 | Royal High (EL1) (H) |
| 5 Mar 2022 | Haddington (EL1) (A) |
| 26 Mar 2022 | Linlithgow (EL1) (H) |